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amitriptyline amt  (Cayman Chemical)


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    Structured Review

    Cayman Chemical amitriptyline amt
    Antidepressant activity of BP (50, 100, and 200 mg/kg p.o.) was evaluated in FST ( A ), TST ( B ), and the mechanism of action of BP with inhibitors in the TST ( C ). The reference drug was 25 mg/kg p.o. <t>amitriptyline</t> <t>(AMT).</t> The results of all experimental groups are reported as the mean values (±SEM) (n = 8). Data were analyzed using a one-way analysis of variance (ANOVA) followed by Tukey post hoc tests. In the FST: a p < 0.05 vs. the vehicle group, and b p < 0.05 vs. the BP group at the dose of 50 mg/kg. In the TST: a p < 0.0001 vs. the vehicle group. In C: a p = 0.0090 vs. the vehicle group.
    Amitriptyline Amt, supplied by Cayman Chemical, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/amitriptyline+amt/pmc12943633-274-34-38?v=Cayman+Chemical
    Average 94 stars, based on 1 article reviews
    amitriptyline amt - by Bioz Stars, 2026-07
    94/100 stars

    Images

    1) Product Images from "Antidepressant-Like Effects of n -Butylidenephthalide Using In Vivo and In Silico Approaches"

    Article Title: Antidepressant-Like Effects of n -Butylidenephthalide Using In Vivo and In Silico Approaches

    Journal: Pharmaceuticals

    doi: 10.3390/ph19020242

    Antidepressant activity of BP (50, 100, and 200 mg/kg p.o.) was evaluated in FST ( A ), TST ( B ), and the mechanism of action of BP with inhibitors in the TST ( C ). The reference drug was 25 mg/kg p.o. amitriptyline (AMT). The results of all experimental groups are reported as the mean values (±SEM) (n = 8). Data were analyzed using a one-way analysis of variance (ANOVA) followed by Tukey post hoc tests. In the FST: a p < 0.05 vs. the vehicle group, and b p < 0.05 vs. the BP group at the dose of 50 mg/kg. In the TST: a p < 0.0001 vs. the vehicle group. In C: a p = 0.0090 vs. the vehicle group.
    Figure Legend Snippet: Antidepressant activity of BP (50, 100, and 200 mg/kg p.o.) was evaluated in FST ( A ), TST ( B ), and the mechanism of action of BP with inhibitors in the TST ( C ). The reference drug was 25 mg/kg p.o. amitriptyline (AMT). The results of all experimental groups are reported as the mean values (±SEM) (n = 8). Data were analyzed using a one-way analysis of variance (ANOVA) followed by Tukey post hoc tests. In the FST: a p < 0.05 vs. the vehicle group, and b p < 0.05 vs. the BP group at the dose of 50 mg/kg. In the TST: a p < 0.0001 vs. the vehicle group. In C: a p = 0.0090 vs. the vehicle group.

    Techniques Used: Activity Assay

    Effect of BP in the Novelty-Suppressed Feeding Test. The parameters evaluated were ( A ) latency time, ( B ) time spent eating, and ( C ) amount of food consumed. The abbreviations of AMT and BP correspond to amitriptyline (positive) and butylidenephthalide, respectively. The results are reported with the mean ± standard error mean (SEM) (n = 6–8). All data were analyzed using a one-way analysis of variance (ANOVA) followed by Dunnett post hoc tests. The “a” letter means statistical difference ( p < 0.05) versus the vehicle group.
    Figure Legend Snippet: Effect of BP in the Novelty-Suppressed Feeding Test. The parameters evaluated were ( A ) latency time, ( B ) time spent eating, and ( C ) amount of food consumed. The abbreviations of AMT and BP correspond to amitriptyline (positive) and butylidenephthalide, respectively. The results are reported with the mean ± standard error mean (SEM) (n = 6–8). All data were analyzed using a one-way analysis of variance (ANOVA) followed by Dunnett post hoc tests. The “a” letter means statistical difference ( p < 0.05) versus the vehicle group.

    Techniques Used:

    Behavioral tests of the reserpine-induced chronic depression model. The figures ( A – D ) correspond to the TST, FST, ECT, and rotarod tests, respectively. The abbreviations V, RS, BP, and AMT correspond to vehicle, reserpine, butylidenephthalide (BP), and amitriptyline, respectively. The results are reported with the mean ± standard error of the mean (SEM) (n = 10). Data were analyzed using a one-way analysis of variance (ANOVA) followed by Tukey post hoc tests. The “a” letter means statistical difference ( p < 0.05) versus the vehicle group not treated with reserpine, “b” means statistical difference versus the vehicle group pretreated with reserpine ( p < 0.05), and “c” means statistical difference versus the AMT group ( p < 0.05).
    Figure Legend Snippet: Behavioral tests of the reserpine-induced chronic depression model. The figures ( A – D ) correspond to the TST, FST, ECT, and rotarod tests, respectively. The abbreviations V, RS, BP, and AMT correspond to vehicle, reserpine, butylidenephthalide (BP), and amitriptyline, respectively. The results are reported with the mean ± standard error of the mean (SEM) (n = 10). Data were analyzed using a one-way analysis of variance (ANOVA) followed by Tukey post hoc tests. The “a” letter means statistical difference ( p < 0.05) versus the vehicle group not treated with reserpine, “b” means statistical difference versus the vehicle group pretreated with reserpine ( p < 0.05), and “c” means statistical difference versus the AMT group ( p < 0.05).

    Techniques Used:



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    Image Search Results


    Antidepressant activity of BP (50, 100, and 200 mg/kg p.o.) was evaluated in FST ( A ), TST ( B ), and the mechanism of action of BP with inhibitors in the TST ( C ). The reference drug was 25 mg/kg p.o. amitriptyline (AMT). The results of all experimental groups are reported as the mean values (±SEM) (n = 8). Data were analyzed using a one-way analysis of variance (ANOVA) followed by Tukey post hoc tests. In the FST: a p < 0.05 vs. the vehicle group, and b p < 0.05 vs. the BP group at the dose of 50 mg/kg. In the TST: a p < 0.0001 vs. the vehicle group. In C: a p = 0.0090 vs. the vehicle group.

    Journal: Pharmaceuticals

    Article Title: Antidepressant-Like Effects of n -Butylidenephthalide Using In Vivo and In Silico Approaches

    doi: 10.3390/ph19020242

    Figure Lengend Snippet: Antidepressant activity of BP (50, 100, and 200 mg/kg p.o.) was evaluated in FST ( A ), TST ( B ), and the mechanism of action of BP with inhibitors in the TST ( C ). The reference drug was 25 mg/kg p.o. amitriptyline (AMT). The results of all experimental groups are reported as the mean values (±SEM) (n = 8). Data were analyzed using a one-way analysis of variance (ANOVA) followed by Tukey post hoc tests. In the FST: a p < 0.05 vs. the vehicle group, and b p < 0.05 vs. the BP group at the dose of 50 mg/kg. In the TST: a p < 0.0001 vs. the vehicle group. In C: a p = 0.0090 vs. the vehicle group.

    Article Snippet: n-Butylidenephthalide (BP) (95% purity) was from Santa Cruz Biotechnology (Santa Cruz, CA, USA); dimethyl sulfoxide (DMSO), TPA (12-O-tetradecanoylphorbol-13-acetate), pentylenetetrazol, pentobarbital, ketanserin, prazosin, and reserpine (RES) were obtained from Sigma-Aldrich (St. Louis, MO, USA); and amitriptyline (AMT) was from Cayman Chemical (Ann Arbor, MI, USA).

    Techniques: Activity Assay

    Effect of BP in the Novelty-Suppressed Feeding Test. The parameters evaluated were ( A ) latency time, ( B ) time spent eating, and ( C ) amount of food consumed. The abbreviations of AMT and BP correspond to amitriptyline (positive) and butylidenephthalide, respectively. The results are reported with the mean ± standard error mean (SEM) (n = 6–8). All data were analyzed using a one-way analysis of variance (ANOVA) followed by Dunnett post hoc tests. The “a” letter means statistical difference ( p < 0.05) versus the vehicle group.

    Journal: Pharmaceuticals

    Article Title: Antidepressant-Like Effects of n -Butylidenephthalide Using In Vivo and In Silico Approaches

    doi: 10.3390/ph19020242

    Figure Lengend Snippet: Effect of BP in the Novelty-Suppressed Feeding Test. The parameters evaluated were ( A ) latency time, ( B ) time spent eating, and ( C ) amount of food consumed. The abbreviations of AMT and BP correspond to amitriptyline (positive) and butylidenephthalide, respectively. The results are reported with the mean ± standard error mean (SEM) (n = 6–8). All data were analyzed using a one-way analysis of variance (ANOVA) followed by Dunnett post hoc tests. The “a” letter means statistical difference ( p < 0.05) versus the vehicle group.

    Article Snippet: n-Butylidenephthalide (BP) (95% purity) was from Santa Cruz Biotechnology (Santa Cruz, CA, USA); dimethyl sulfoxide (DMSO), TPA (12-O-tetradecanoylphorbol-13-acetate), pentylenetetrazol, pentobarbital, ketanserin, prazosin, and reserpine (RES) were obtained from Sigma-Aldrich (St. Louis, MO, USA); and amitriptyline (AMT) was from Cayman Chemical (Ann Arbor, MI, USA).

    Techniques:

    Behavioral tests of the reserpine-induced chronic depression model. The figures ( A – D ) correspond to the TST, FST, ECT, and rotarod tests, respectively. The abbreviations V, RS, BP, and AMT correspond to vehicle, reserpine, butylidenephthalide (BP), and amitriptyline, respectively. The results are reported with the mean ± standard error of the mean (SEM) (n = 10). Data were analyzed using a one-way analysis of variance (ANOVA) followed by Tukey post hoc tests. The “a” letter means statistical difference ( p < 0.05) versus the vehicle group not treated with reserpine, “b” means statistical difference versus the vehicle group pretreated with reserpine ( p < 0.05), and “c” means statistical difference versus the AMT group ( p < 0.05).

    Journal: Pharmaceuticals

    Article Title: Antidepressant-Like Effects of n -Butylidenephthalide Using In Vivo and In Silico Approaches

    doi: 10.3390/ph19020242

    Figure Lengend Snippet: Behavioral tests of the reserpine-induced chronic depression model. The figures ( A – D ) correspond to the TST, FST, ECT, and rotarod tests, respectively. The abbreviations V, RS, BP, and AMT correspond to vehicle, reserpine, butylidenephthalide (BP), and amitriptyline, respectively. The results are reported with the mean ± standard error of the mean (SEM) (n = 10). Data were analyzed using a one-way analysis of variance (ANOVA) followed by Tukey post hoc tests. The “a” letter means statistical difference ( p < 0.05) versus the vehicle group not treated with reserpine, “b” means statistical difference versus the vehicle group pretreated with reserpine ( p < 0.05), and “c” means statistical difference versus the AMT group ( p < 0.05).

    Article Snippet: n-Butylidenephthalide (BP) (95% purity) was from Santa Cruz Biotechnology (Santa Cruz, CA, USA); dimethyl sulfoxide (DMSO), TPA (12-O-tetradecanoylphorbol-13-acetate), pentylenetetrazol, pentobarbital, ketanserin, prazosin, and reserpine (RES) were obtained from Sigma-Aldrich (St. Louis, MO, USA); and amitriptyline (AMT) was from Cayman Chemical (Ann Arbor, MI, USA).

    Techniques:

    Data of four APIs and tentatively identified metabolites. If no CCS values are provided, the ion abundance was too low for accurate CCS determination

    Journal: Environmental Science and Pollution Research International

    Article Title: Uptake, translocation, and metabolization of amitriptyline, lidocaine, orphenadrine, and tramadol by cress and pea

    doi: 10.1007/s11356-024-32379-x

    Figure Lengend Snippet: Data of four APIs and tentatively identified metabolites. If no CCS values are provided, the ion abundance was too low for accurate CCS determination

    Article Snippet: Amitriptyline hydrochloride (AMT) (Lundbeck AG, Opficon, Switzerland), orphenadrine citrate (ORP) (Meda Pharma GmbH, Vienna, Austria), and tramadol hydrochloride (TRM) (Ratiopharm GmbH, Ulm, Germany) were obtained as pharmaceutical preparation.

    Techniques: